{"id":1386,"date":"2014-09-01T12:39:36","date_gmt":"2014-09-01T12:39:36","guid":{"rendered":"http:\/\/gnathologio.gr\/?p=1386"},"modified":"2015-01-01T15:06:00","modified_gmt":"2015-01-01T15:06:00","slug":"%ce%bc%ce%b9%ce%b1-%cf%80%ce%b5%cf%81%ce%af%cf%80%cf%84%cf%89%cf%83%ce%b7-%ce%b1%cf%80%ce%bf%cf%84%cf%85%cf%87%ce%af%ce%b1%cf%82-%ce%bf%ce%b4%ce%bf%ce%bd%cf%84%ce%b9%ce%ba%cf%8e%ce%bd-%ce%b5%ce%bc","status":"publish","type":"post","link":"https:\/\/gnathion.gr\/mag\/?p=1386","title":{"rendered":"\u039c\u03b9\u03b1 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03bb\u03ae\u03c8\u03b7\u03c2 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2(Prolia)"},"content":{"rendered":"<p><a href=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-1387\" src=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11-300x237.jpg\" alt=\"11\" width=\"300\" height=\"237\" srcset=\"https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11-300x237.jpg 300w, https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11.jpg 743w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a>\u0397 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7(denosumab, Prolia) \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03bd\u03ad\u03bf \u03b1\u03bd\u03c4\u03b9\u03bf\u03c3\u03c4\u03b5\u03bf\u03bb\u03c5\u03c4\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03c7\u03bf\u03c1\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03cc\u03c1\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03bc\u03b5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1\u03c2. \u039c\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bb\u03ae\u03c8\u03b7 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03bf\u03c3\u03c4\u03b5\u03bf\u03bd\u03ad\u03ba\u03c1\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b1 \u03bf\u03c3\u03c4\u03ac \u03c4\u03c9\u03bd \u03b3\u03bd\u03ac\u03b8\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b1 \u03b4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bd\u03b9\u03ba\u03ac(<strong>1<\/strong>).<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b5\u03bd\u03ce \u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bd\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03b1 \u03bf\u03c3\u03c4\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1(<strong>2-4<\/strong>), \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2, \u03bb\u03cc\u03b3\u03c9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2, \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 6 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03c3\u03c4\u03bf 53% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03b4\u03b5\u03bd \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ac, \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 9 \u03bc\u03ae\u03bd\u03b5\u03c2, \u03bf\u03b9 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b5\u03bd\u03b1\u03bb\u03bb\u03b1\u03b3\u03ae\u03c2 \u03b5\u03c0\u03b1\u03bd\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c0\u03c1\u03bf \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2(<strong>1<\/strong>).<\/p>\n<p>\u0397 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7 \u03c3\u03c4\u03b7\u03bd \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03c4\u03c9\u03bd \u03b3\u03bd\u03ac\u03b8\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7(<strong>5-11<\/strong>) \u03b5\u03bd\u03ce \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03ae \u03c4\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b5\u03bf\u03b5\u03bd\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd(<strong>12<\/strong>). \u03a0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03c5\u03bc\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03b4\u03cd\u03bf \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd, \u03c0\u03bf\u03c5 \u03c4\u03bf\u03c0\u03bf\u03b8\u03b5\u03c4\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd 12 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03bc\u03b9\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03ae\u03c2 \u03b5\u03be\u03b1\u03bc\u03b7\u03bd\u03b9\u03b1\u03af\u03b1\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7\u03c2<\/strong><\/p>\n<p>\u0393\u03c5\u03bd\u03b1\u03af\u03ba\u03b1, 64\u00a0 \u03b5\u03c4\u03ce\u03bd, \u03bc\u03b5 \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03bf \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03c0\u03c1\u03bf\u03c3\u03ae\u03bb\u03b8\u03b5 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c0\u03bf\u03b8\u03ad\u03c4\u03b7\u03c3\u03b7 \u03b4\u03cd\u03bf \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u03ba\u03ac\u03c4\u03c9 \u03b3\u03bd\u03ac\u03b8\u03bf, \u03b4\u03b5\u03be\u03b9\u03ac. \u03a3\u03c4\u03b7\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03b5\u03af\u03c7\u03b5 \u03c7\u03bf\u03c1\u03b7\u03b3\u03b7\u03b8\u03b5\u03af, 12 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03ad\u03bb\u03b5\u03c5\u03c3\u03b7, \u03bc\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2 (Prolia),(60 mg \u03a5\u0394, \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03c5\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03bb\u03ae\u03c8\u03b7 \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5) \u03b3\u03b9\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03cc\u03c1\u03c9\u03c3\u03b7\u03c2.<\/p>\n<p>\u0397 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2, \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03bc\u03b5 Prolia, \u03b5\u03af\u03c7\u03b5 \u03c5\u03c0\u03bf\u03b2\u03bb\u03b7\u03b8\u03b5\u03af \u03bc\u03b5 \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1 \u03c3\u03b5 \u03c4\u03bf\u03c0\u03bf\u03b8\u03ad\u03c4\u03b7\u03c3\u03b7 \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u03ac\u03bd\u03c9 \u03b3\u03bd\u03ac\u03b8\u03bf, \u03b1\u03c1\u03b9\u03c3\u03c4\u03b5\u03c1\u03ac(\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1). \u0394\u03b5\u03bd \u03b5\u03af\u03c7\u03b5 \u03bb\u03ac\u03b2\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03ba\u03b1\u03b9 10 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bb\u03ae\u03c8\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b5\u03af\u03c7\u03b5 \u03c5\u03c0\u03bf\u03b2\u03bb\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03b4\u03cd\u03bf \u03b5\u03be\u03b1\u03b3\u03c9\u03b3\u03ad\u03c2(#46, #37) \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2.<\/p>\n<figure id=\"attachment_1388\" aria-describedby=\"caption-attachment-1388\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11a.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1388\" src=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11a-300x174.jpg\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1\" width=\"300\" height=\"174\" srcset=\"https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11a-300x174.jpg 300w, https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11a.jpg 951w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-1388\" class=\"wp-caption-text\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1<\/figcaption><\/figure>\n<p>\u0391\u03c0\u03cc \u03c4\u03b7\u03bd 15\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u039c.\u0397 \u03b7 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03b1\u03bd\u03ad\u03c6\u03b5\u03c1\u03b5 \u03ae\u03c0\u03b9\u03bf \u03b1\u03bb\u03bb\u03ac \u03c3\u03c5\u03bd\u03b5\u03c7\u03ad\u03c2 \u03ac\u03bb\u03b3\u03bf\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7, \u03c4\u03b7\u03bd 20\u03b7 \u039c.\u0397, \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ba\u03b1\u03b9 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03cd\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c3\u03c4\u03b7 \u03b8\u03ad\u03c3\u03b7 #45, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03b1\u03c6\u03b1\u03b9\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5. \u03a4\u03bf \u03ac\u03bb\u03b3\u03bf\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bc\u03af\u03b1 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7 \u03b2\u03bb\u03ac\u03b2\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b8\u03ad\u03c3\u03b7\u03c2 #47, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c6\u03b1\u03b9\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5. \u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03be\u03b5\u03c3\u03b7, \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b8\u03ad\u03c3\u03b7 #45, \u03b1\u03c6\u03b1\u03b9\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc \u03bf\u03c3\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03cc\u03bb\u03c5\u03bc\u03bc\u03b1.\u03a4\u03bf\u03c0\u03bf\u03b8\u03b5\u03c4\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b4\u03cd\u03bf \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ac \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1, \u03ad\u03bd\u03b1 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b8\u03ad\u03c3\u03b7 #45(4.5\/13 Xive, Dentsply) \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03bf\u03c5 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03c5 \u03b4\u03bf\u03bd\u03c4\u03b9\u03bf\u03cd \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b8\u03ad\u03c3\u03b7 #47(3.8\/13 Xive, Dentsply). \u0397 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2, \u03c5\u03c0\u03cc \u03b1\u03bd\u03c4\u03b9\u03b2\u03af\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c7\u03bb\u03c9\u03c1\u03b5\u03be\u03b9\u03b4\u03af\u03bd\u03b7\u03c2, \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u03c3\u03b5 \u03bf\u03bc\u03b1\u03bb\u03ae \u03bc\u03b5\u03c4\u03b5\u03b3\u03c7\u03b5\u03b9\u03c1\u03b7\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03c1\u03ac\u03bc\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c6\u03b1\u03b9\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03c4\u03b7\u03bd 8\u03b7 \u039c.\u0397.<\/p>\n<p>\u03a3\u03c4\u03b7\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03bd\u03c4\u03b9\u03b2\u03af\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bc\u03b1\u03c4\u03bf\u03c0\u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5 \u03c7\u03bb\u03c9\u03c1\u03b5\u03be\u03b9\u03b4\u03af\u03bd\u03b7. \u03a3\u03c4\u03b7\u03bd \u03c0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b5\u03ba\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b5\u03bf\u03bb\u03c5\u03c3\u03af\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03b1\u03c6\u03b1\u03b9\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03c4\u03b1 \u03b4\u03cd\u03bf \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ac \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03bf\u03bd \u03b5\u03bd\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03bf \u03c7\u03ce\u03c1\u03bf(\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 2). \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b4\u03b5\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03b1\u03c0\u03bf\u03b3\u03c5\u03bc\u03bd\u03c9\u03bc\u03ad\u03bd\u03bf \u03bf\u03c3\u03c4\u03bf\u03cd\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03c0\u03bf\u03cd\u03bb\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bc\u03b1\u03bb\u03b1\u03ba\u03ce\u03bd \u03bc\u03bf\u03c1\u03af\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae\u03c2 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1 \u03bc\u03ae\u03bd\u03b1.<\/p>\n<figure id=\"attachment_1389\" aria-describedby=\"caption-attachment-1389\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11b.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1389\" src=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11b-300x172.jpg\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 2. \u03a0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u0391\/\u0391 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd(\u03ba\u03af\u03c4\u03c1\u03b9\u03bd\u03b1 \u03b2\u03ad\u03bb\u03b7) \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1(\u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03b1 \u03b2\u03ad\u03bb\u03b7).\" width=\"300\" height=\"172\" srcset=\"https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11b-300x172.jpg 300w, https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11b.jpg 950w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-1389\" class=\"wp-caption-text\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 2. \u03a0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u0391\/\u0391 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1\u03c2 \u03c4\u03c9\u03bd \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd(\u03ba\u03af\u03c4\u03c1\u03b9\u03bd\u03b1 \u03b2\u03ad\u03bb\u03b7) \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1(\u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03b1 \u03b2\u03ad\u03bb\u03b7).<\/figcaption><\/figure>\n<p>\u0397 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b5\u03b9\u03bd\u03b5 \u03b1\u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 8 \u03bc\u03ae\u03bd\u03b5\u03c2, \u03c3\u03b5 \u03bd\u03ad\u03b1 \u03c0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1, \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5, \u03c3\u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae, \u03b7 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b4\u03bf\u03ba\u03af\u03b4\u03c9\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c3\u03c4\u03bf\u03cd \u03c4\u03b7\u03c2 \u03ba\u03ac\u03c4\u03c9 \u03b3\u03bd\u03ac\u03b8\u03bf\u03c5(\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 3). \u0397 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2 \u03bc\u03b5 \u03b4\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03b5\u03af\u03c7\u03b5 \u03c0\u03bb\u03ad\u03bf\u03bd \u03b4\u03b9\u03b1\u03ba\u03cc\u03c8\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac \u03b3\u03b9\u03b1 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03ad\u03bd\u03b1 \u03c7\u03c1\u03cc\u03bd\u03bf \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c6\u03ac\u03c3\u03b9\u03c3\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03b5\u03c0\u03b1\u03bd\u03b1\u03c4\u03bf\u03c0\u03bf\u03b8\u03ad\u03c4\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n<figure id=\"attachment_1390\" aria-describedby=\"caption-attachment-1390\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11c.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1390\" src=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11c-300x172.jpg\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 3. \u03a0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u0391\/\u0391 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03bc\u03b1\u03bb\u03ae\u03c2 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c5\u03c6\u03ae\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae \u03c4\u03b7\u03c2 \u03ba\u03ac\u03c4\u03c9 \u03b3\u03bd\u03ac\u03b8\u03bf\u03c5 \u03b4\u03b5\u03be\u03b9\u03ac (\u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03b7 \u03c9\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae)\" width=\"300\" height=\"172\" srcset=\"https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11c-300x172.jpg 300w, https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11c.jpg 944w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-1390\" class=\"wp-caption-text\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 3. \u03a0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u0391\/\u0391 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03bc\u03b1\u03bb\u03ae\u03c2 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c5\u03c6\u03ae\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae \u03c4\u03b7\u03c2 \u03ba\u03ac\u03c4\u03c9 \u03b3\u03bd\u03ac\u03b8\u03bf\u03c5 \u03b4\u03b5\u03be\u03b9\u03ac (\u03ba\u03cc\u03ba\u03ba\u03b9\u03bd\u03b7 \u03c9\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae)<\/figcaption><\/figure>\n<p>\u03a4\u03bf\u03c0\u03bf\u03b8\u03b5\u03c4\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b4\u03cd\u03bf \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1 (3,8\/13 \u03ba\u03b1\u03b9 4.5\/13 Xive, Dentsply)(\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 4).<\/p>\n<figure id=\"attachment_1391\" aria-describedby=\"caption-attachment-1391\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11d.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1391\" src=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11d-300x182.jpg\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 4. \u03a0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u0391\/\u0391 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03bd\u03ad\u03c9\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd (\u03ba\u03af\u03c4\u03c1\u03b9\u03bd\u03b1 \u03b2\u03ad\u03bb\u03b7)\" width=\"300\" height=\"182\" srcset=\"https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11d-300x182.jpg 300w, https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11d.jpg 949w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-1391\" class=\"wp-caption-text\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 4. \u03a0\u03b1\u03bd\u03bf\u03c1\u03b1\u03bc\u03b9\u03ba\u03ae \u0391\/\u0391 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03bd\u03ad\u03c9\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd (\u03ba\u03af\u03c4\u03c1\u03b9\u03bd\u03b1 \u03b2\u03ad\u03bb\u03b7)<\/figcaption><\/figure>\n<p>\u0394\u03c5\u03cc\u03bc\u03b9\u03c3\u03b7 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac, \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03bf\u03ba\u03ac\u03bb\u03c5\u03c8\u03b7\u03c2, \u03b1\u03c6\u03b1\u03b9\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03bf #44.\u00a0\u0397 \u03cc\u03bb\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03ae\u03c4\u03b1\u03bd \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03ce\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae\u03c2(\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 5).<\/p>\n<figure id=\"attachment_1392\" aria-describedby=\"caption-attachment-1392\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11e.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1392\" src=\"http:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11e-300x209.jpg\" alt=\"\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 5. \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03c9\u03bd \u03bf\u03c3\u03c4\u03b5\u03bf\u03b5\u03bd\u03c3\u03c9\u03bc\u03b1\u03c4\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03c7\u03bb\u03b9\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b9\u03c2 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bc\u03c6\u03c1\u03ac\u03be\u03b5\u03b9\u03c2 (\u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03a0\u03c1\u03bf\u03c3\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae: Dr. \u0391. \u03a1\u03ae\u03b3\u03b1).\" width=\"300\" height=\"209\" srcset=\"https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11e-300x209.jpg 300w, https:\/\/gnathion.gr\/mag\/wp-content\/uploads\/2014\/08\/11e.jpg 813w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-1392\" class=\"wp-caption-text\">\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 5. \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03c9\u03bd \u03bf\u03c3\u03c4\u03b5\u03bf\u03b5\u03bd\u03c3\u03c9\u03bc\u03b1\u03c4\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03c7\u03bb\u03b9\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b9\u03c2 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bc\u03c6\u03c1\u03ac\u03be\u03b5\u03b9\u03c2 (\u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03a0\u03c1\u03bf\u03c3\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae: Dr. \u0391. \u03a1\u03ae\u03b3\u03b1).<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p><strong>\u03a3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7<\/strong><\/p>\n<p>\u03a4\u03bf \u03bc\u03cc\u03c1\u03b9\u03bf RANKL (Receptor Activator of nuclear factor kappa-B ligand\/\u03c3\u03c5\u03bd\u03b4\u03ad\u03c4\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03ae \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03c5\u03c1\u03b7\u03bd\u03b9\u03ba\u03bf\u03cd \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03ba\u03ac\u03c0\u03c0\u03b1-\u03b2) \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 \u03bf\u03c3\u03c4\u03b5\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03b5\u03cc\u03bc\u03b5\u03bd\u03bf \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03b1 RANK, \u03c0\u03bf\u03c5 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b1 \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03b4\u03c1\u03cc\u03bc\u03c9\u03bd \u03bc\u03bf\u03c1\u03c6\u03ce\u03bd \u03c4\u03c9\u03bd \u03bf\u03c3\u03c4\u03b5\u03bf\u03ba\u03bb\u03b1\u03c3\u03c4\u03ce\u03bd \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7, \u03c4\u03b7\u03bd \u03c9\u03c1\u03af\u03bc\u03b1\u03bd\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5\u03c2(<strong>5<\/strong>).<\/p>\n<p>\u039f\u03b9 \u03bf\u03c3\u03c4\u03b5\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03b5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03ac\u03bb\u03bb\u03bf \u03bc\u03cc\u03c1\u03b9\u03bf, \u03c4\u03bf OPG (osteoprotegerin-\u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03c1\u03bf\u03c4\u03b5\u03b3\u03b5\u03c1\u03af\u03bd\u03b7), \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03b4\u03c1\u03b1 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7, \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 RANKL, \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03bf \u03b3\u03b9\u03b1 \u03b4\u03ad\u03c3\u03bc\u03b5\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 RANK(<strong>5<\/strong>).<\/p>\n<p>\u0397 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7(denosumab) \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c3\u03c6\u03b1\u03c1\u03af\u03bd\u03b7(IgG2), \u03c0\u03bf\u03c5 \u03bc\u03b9\u03bc\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03c4\u03b7\u03bd \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03c1\u03bf\u03c4\u03b5\u03b3\u03b5\u03c1\u03af\u03bd\u03b7\u03c2, \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9, \u03ba\u03b1\u03b9 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03c5\u03b3\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03bc\u03b5 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\u03b1\u03c0\u03cc \u03ad\u03bd\u03b1\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03c4\u03bf\u03c0\u03bf\u03b8\u03b5\u03c4\u03b7\u03b8\u03bf\u03cd\u03bd \u03bc\u03b5 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03c4\u03b1 \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ac \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1. \u03a0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03b4\u03b9\u03b5\u03be\u03b1\u03c7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd \u03b8\u03b1 \u03b4\u03ce\u03c3\u03bf\u03c5\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03ac \u03c0\u03b9\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c3\u03c6\u03b1\u03bb\u03b5\u03af\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/p>\n<p>\u03a0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03c0\u03b1\u03c1\u03cc\u03bd, \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b7 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03bf\u03c0\u03b1\u03b8\u03ce\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd, \u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bd \u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03bb\u03ae\u03c8\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03bf\u03c3\u03c4\u03b5\u03bf\u03bb\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5(\u03b4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bd\u03b9\u03ba\u03ac) \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03c0\u03cc \u03b4\u03cd\u03bf \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1, \u03cc\u03c4\u03b9 \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c2 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf \u03c3\u03c4\u03cc\u03bc\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03be\u03b1\u03b3\u03c9\u03b3\u03ad\u03c2, \u03b1\u03ba\u03c1\u03bf\u03c1\u03c1\u03b9\u03b6\u03b5\u03ba\u03c4\u03bf\u03bc\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ac \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03cd\u03bc\u03b1\u03c4\u03b1(<strong>13<\/strong>).<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03cc\u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b4\u03b9\u03ba\u03ae \u03bc\u03b1\u03c2 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7, \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ce\u03bd, \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ac \u03b7 \u03b1\u03c0\u03cc\u03c6\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03bf\u03c3\u03c4\u03b5\u03bf\u03bb\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03bd\u03b1 \u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03c4\u03bf\u03bd \u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03cc \u03ba\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03bf\u03bd \u03c5\u03c0\u03b1\u03c1\u03ba\u03c4\u03cc, \u03b1\u03bb\u03bb\u03ac \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bc\u03b7 \u03bf\u03c3\u03c4\u03b5\u03bf\u03b5\u03bd\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7 \u03ae \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bf\u03c3\u03c4\u03b5\u03bf\u03bd\u03ad\u03ba\u03c1\u03c9\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b3\u03bd\u03ac\u03b8\u03bf\u03c5\u03c2(<strong>13<\/strong>), \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2, \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc\u03bb\u03c5\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae\u03c2.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/strong><\/p>\n<p>(<strong>1<\/strong>)\u00a0<a href=\"http:\/\/ec.europa.eu\/health\/documents\/community-register\/2010\/2010052679008\/anx_79008_en.pdf\">Prolia, INN-denosumab \u2013 Europa.<\/a><\/p>\n<p>(<strong>2<\/strong>) Malan J, Ettinger K, Naumann E, Beirne OR.\u00a0The relationship of denosumab pharmacology and osteonecrosis of the jaws.\u00a0Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Dec;114(6):671-6.<\/p>\n<p>(<strong>3<\/strong>) Drake MT, Clarke BL, Khosla S.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2667901\/\">Bisphosphonates: mechanism of action and role in clinical practice.<\/a>\u00a0Mayo Clin Proc. 2008 Sep;83(9):1032-45.<\/p>\n<p>(<strong>4<\/strong>) Gordon J Strewler.\u00a0<a href=\"http:\/\/www.nature.com\/bonekey\/knowledgeenvironment\/2005\/0501\/bonekey20050143\/full\/bonekey20050143.html\">Long-term bisphosphonates for osteoporosis: An introduction<\/a>, BoneKEy-Osteovision (2005) 2, 6\u20139.<\/p>\n<p>(<strong>5<\/strong>) Epstein MS, Ephros HD, Epstein JB.\u00a0Review of current literature and implications of RANKL inhibitors for oral health care providers. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Dec;116(6):e437-42.<\/p>\n<p>(<strong>6<\/strong>)\u00a0Aghaloo TL, Felsenfeld AL, Tetradis S.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2880179\/\">Osteonecrosis of the jaw in a patient on Denosumab.<\/a>\u00a0 J Oral Maxillofac Surg. 2010 May;68(5):959-63.<\/p>\n<p>(<strong>7<\/strong>) Rachner TD, Platzbecker U, Felsenberg D, Hofbauer LC.\u00a0Osteonecrosis of the jaw after osteoporosis therapy with denosumab following long-term bisphosphonate therapy.\u00a0Mayo Clin Proc. 2013 Apr;88(4):418-9.<\/p>\n<p>(<strong>8<\/strong>) Aghaloo TL, Cheong S, Bezouglaia O, Kostenuik P, Atti E, Dry SM, Pirih FQ, Tetradis S. RANKL inhibitors induce osteonecrosis of the jaw in mice with periapical disease.\u00a0J Bone Miner Res. 2014 Apr;29(4):843-54.<\/p>\n<p>(<strong>9<\/strong>)\u00a0 Diz P, L\u00f3pez-Cedr\u00fan JL, Arenaz J, Scully C. Denosumab-related osteonecrosis of the jaw.\u00a0J Am Dent Assoc. 2012 Sep;143(9):981-4.<\/p>\n<p>(<strong>10<\/strong>)Vyas S, Hameed S, Murugaraj V. Denosumab-associated osteonecrosis of the jaw&#8211;a case report.\u00a0Dent Update. 2014 Jun;41(5):449-50.<\/p>\n<p>(<strong>11<\/strong>) Neuprez A, Coste S, Rompen E, Crielaard JM, Reginster JY. Osteonecrosis of the jaw in a male osteoporotic patient treated with denosumab.\u00a0Osteoporos Int. 2014 Jan;25(1):393-5.<\/p>\n<p>(<strong>12<\/strong>) Anastasilakis AD, Toulis KA, Polyzos SA, Anastasilakis CD, Makras P. Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab.\u00a0Ther Clin Risk Manag. 2012;8:295-306.<\/p>\n<p>(<strong>13<\/strong>) Hellstein JW, Adler RA, Edwards B, Jacobsen PL, Kalmar JR, Koka S, Migliorati \u00a0CA, Ristic H; American Dental Association Council on Scientific Affairs Expert Panel on Antiresorptive Agents.\u00a0<a href=\"http:\/\/jada.ada.org\/content\/142\/11\/1243.full.pdf\">Managing the care of patients receiving antiresorptive therapy for prevention andtreatment of osteoporosis: executive summary of recommendations from the AmericanDental Association Council on Scientific Affairs.<\/a>\u00a0J Am Dent Assoc. 2011 Nov;142(11):1243-51.<\/p>\n<p>(<strong>14<\/strong>) Yip JK, Borrell LN, Cho SC, Francisco H, Tarnow DP. Association between oral bisphosphonate use and dental implant failure among middle-aged women. J Clin\u00a0Periodontol. 2012 pr;39(4):408-14.<\/p>\n<p>\u0394\u03a4<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0397 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7(denosumab, Prolia) \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03bd\u03ad\u03bf \u03b1\u03bd\u03c4\u03b9\u03bf\u03c3\u03c4\u03b5\u03bf\u03bb\u03c5\u03c4\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03c7\u03bf\u03c1\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03cc\u03c1\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03bc\u03b5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1\u03c2. \u039c\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bb\u03ae\u03c8\u03b7 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"more-link\" href=\"https:\/\/gnathion.gr\/mag\/?p=1386\"> <span class=\"screen-reader-text\">\u039c\u03b9\u03b1 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03bf\u03b4\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03bc\u03ac\u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03bb\u03ae\u03c8\u03b7\u03c2 \u03b4\u03b5\u03bd\u03bf\u03c3\u03bf\u03c5\u03bc\u03ac\u03bc\u03c0\u03b7\u03c2(Prolia)<\/span> Read More &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-1386","post","type-post","status-publish","format-standard","hentry","category-inter_case"],"_links":{"self":[{"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=\/wp\/v2\/posts\/1386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1386"}],"version-history":[{"count":8,"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=\/wp\/v2\/posts\/1386\/revisions"}],"predecessor-version":[{"id":29590,"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=\/wp\/v2\/posts\/1386\/revisions\/29590"}],"wp:attachment":[{"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gnathion.gr\/mag\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}